Formulation Performance
Formulation Performance
Formulation Performance
The performance of a product formulation can be influenced in many ways by the moisture present in the surrounding air.
The stability of these formulations is critical to maintaining their efficacy. Dynamic Vapor Sorption (DVS) and iGC-SEA (Inverse Gas Chromatography – Surface Energy Analyzer) can be used to analyze product drying processes, surface deposition of formulations, adhesive properties of powder blends, and the stabilizing effects of protein stabilizers.
Personal Care
The moisture content of cream-based products such as sunscreens and hand creams is a key factor in determining the sensory feel and texture of the formulation. The rate of moisture loss is a critical property that reflects the overall efficacy of the product.
Dynamic Vapor Sorption (DVS) is used to measure these key factors, evaluating drying rate and total moisture content. In addition, iGC-SEA (Inverse Gas Chromatography – Surface Energy Analyzer) can be used to measure the deposition of products onto key surfaces such as hair fibers.
This highly sensitive instrument detects subtle differences in surface heterogeneity and precisely measures changes in moisture sorption caused by product deposition.
DVS Application Note 29: Moisture Desorption of Creams and Calculation of Diffusion Constants. [Request a copy]
Powder Mixing
Pharmaceutical manufacturing typically involves the dry blending of multiple powders, a process in which the Active Pharmaceutical Ingredient (API) must be uniformly dispersed. Controlling the adhesive forces between the binder and the API is highly important during formulation, as it helps prevent uneven binder distribution and the degradation of tablet mechanical properties.
Inverse Gas Chromatography (IGC) is used to measure the adhesive properties of powders, enabling prediction of blend performance and the mechanical properties of the final formulation. Solid dosage forms must withstand a range of humidity and temperature conditions during storage, ensuring that the active ingredient is delivered in the intended state.
Dynamic Vapor Sorption (DVS) is used to measure phase transitions within the solid excipient structure and identify regions of relative stability. DVS can also analyze the stabilizing effects of protein components added to amorphous excipients, including their role in preventing early-stage material degradation and enhancing the physical stability of the drug.
iGC-SEA Case Study 610: Correlating Mixing Properties of Model Excipient–API Blends to Spreading Coefficients Determined via Inverse Gas Chromatography. [Request a copy]
Polymers
Polymers such as polyolefins are widely used across various industries. Polyolefins have low surface energy, which results in poor adhesion to paints and other composite materials. A variety of techniques are used to increase the surface energy of these polymers and improve their adhesion properties.
iGC-SEA (Inverse Gas Chromatography – Surface Energy Analyzer) provides highly sensitive measurement of polymer surface energy, helping to predict adhesion quality and enhance product performance.
iGC-SEA Case Study 606: Correlating Surface Energies to Adhesion Data for Thermoplastic Polyolefins via Inverse Gas Chromatography. [Request a copy] iGC-SEA Case Study 604: Determination of Carbon Fibre–Polymer Interactions by Inverse Gas Chromatography. [Request a copy]
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Business Registration Number: 314-24-80398
Phone: 031-794-7980 Consultation Hours: Weekdays 09:00–18:00 (Closed on weekends and public holidays)
Formulation Performance
The performance of a product formulation can be influenced in many ways by the moisture present in the surrounding air. The stability of these formulations is critical to maintaining their efficacy. Dynamic Vapor Sorption (DVS) and iGC-SEA (Inverse Gas Chromatography – Surface Energy Analyzer) can be used to analyze product drying processes, surface deposition of formulations, adhesive properties of powder blends, and the stabilizing effects of protein stabilizers.
Personal Care
The moisture content of cream-based products such as sunscreens and hand creams is a key factor in determining the sensory feel and texture of the formulation. The rate of moisture loss is a critical property that reflects the overall efficacy of the product.
Dynamic Vapor Sorption (DVS) is used to measure these key factors, evaluating drying rate and total moisture content. In addition, iGC-SEA (Inverse Gas Chromatography – Surface Energy Analyzer) can be used to measure the deposition of products onto key surfaces such as hair fibers. This highly sensitive instrument detects subtle differences in surface heterogeneity and precisely measures changes in moisture sorption caused by product deposition.
DVS Application Note 29: Moisture Desorption of Creams and Calculation of Diffusion Constants. [Request a copy]
Powder Mixing
Pharmaceutical manufacturing typically involves the dry blending of multiple powders, a process in which the Active Pharmaceutical Ingredient (API) must be uniformly dispersed. Controlling the adhesive forces between the binder and the API is highly important during formulation, as it helps prevent uneven binder distribution and the degradation of tablet mechanical properties.
Inverse Gas Chromatography (IGC) is used to measure the adhesive properties of powders, enabling prediction of blend performance and the mechanical properties of the final formulation. Solid dosage forms must withstand a range of humidity and temperature conditions during storage, ensuring that the active ingredient is delivered in the intended state.
Dynamic Vapor Sorption (DVS) is used to measure phase transitions within the solid excipient structure and identify regions of relative stability. DVS can also analyze the stabilizing effects of protein components added to amorphous excipients, including their role in preventing early-stage material degradation and enhancing the physical stability of the drug.
iGC-SEA Case Study 610: Correlating Mixing Properties of Model Excipient–API Blends to Spreading Coefficients Determined via Inverse Gas Chromatography. [Request a copy]
Polymers
Polymers such as polyolefins are widely used across various industries. Polyolefins have low surface energy, which results in poor adhesion to paints and other composite materials. A variety of techniques are used to increase the surface energy of these polymers and improve their adhesion properties.
iGC-SEA (Inverse Gas Chromatography – Surface Energy Analyzer) provides highly sensitive measurement of polymer surface energy, helping to predict adhesion quality and enhance product performance.
iGC-SEA Case Study 606: Correlating Surface Energies to Adhesion Data for Thermoplastic Polyolefins via Inverse Gas Chromatography. [Request a copy] iGC-SEA Case Study 604: Determination of Carbon Fibre–Polymer Interactions by Inverse Gas Chromatography. [Request a copy]
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Company Name : SNT Address: W 1013, The Front Misa, 11 Misagang-byeonjungang-ro, Hanam-si, Gyeonggi-do
Business Registration Number: 314-24-80398 CEO: Lee Woo-jong Phone: 031-794-7980 Consultation Hours: Weekdays 09:00–18:00 (Closed on weekends and public holidays)
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